Doctor of Philosophy [Ph.D] (KESS2 PhD in Biosciences: Dissecting the biomolecular role of Bcl3 in breast cancer metastasis and the design of new interaction)
3 years
Full Time
Field of Study:
- Progression to metastatic disease is usually a devastating event for most cancer patients here in Wales and throughout the world.
- It is estimated that around 90% of cancer deaths are attributable to poorly treated tumour metastasis, where there are no truly effective drugs in the clinic. In addition, more than 30% of cancer patients will relapse and die because of recurrent metastatic disease despite recent improvements in application of adjuvant therapies.ÊÊ
- Bcl3 is a proto-oncogene that plays a key role in regulating gene expression by controlling the activity of transcription factors, such as the NFkB that regulate a variety of cellular genes, including those associated with cell proliferation, apoptosis and the stress response. Bcl3 has been reported to be deregulated in breast cancer, but its suppression leads to a reduction in the migratory capacity of the bulk of the tumour cells, with a concomitant increase in migration/metastasis inhibitory genes. Based on these findings, Bcl3 was considered as a target for drug development, resulting in some promising therapeutic leads.ÊÊ
Read More
Important Dates
University allocates places on a first-come, first-served basis, so students are recommended to apply as early as possible.
Scholarship Grants & Financial Aids
Name | Scholarship Per Student | Level of Study | Type | |
---|---|---|---|---|
Commonwealth Rutherford Fellowship | Scholarship per student£ 3,105/Yr$3,105 | Level Of StudyDoctorate | TypeMerit-Based | |
Monica Cole Research Grant | Scholarship per student£ 1,291/Yr$1,291 | Level Of StudyApprenticeship | TypeMerit-Based | |
Commonwealth Professional Fellowship | Scholarship per studentVariable Amount | Level Of StudyDoctorate | TypeMerit-Based | |
JN Tata Endowment Scholarship | Scholarship per studentVariable Amount | Level Of StudyDoctorate | TypeMerit-Based | |
Commonwealth Scholarship | Scholarship per studentVariable Amount | Level Of StudyDoctorate | TypeMerit-Based | |
Forktip Women’s- Innovation Scholarship | Scholarship per studentVariable Amount | Level Of StudyBachelor | TypeCollege-Specific |
Similar Colleges
Robert Gordon University
Aberdeen, Scotland
University of Aberdeen
Aberdeen, Scotland
Aberystwyth University
Aberystwyth, Wales
University of Bath
Bath, England
Cranfield University
Bedford, England
Queen's University Belfast
Belfast, Northern Ireland
Ulster University
Belfast, Northern Ireland
University of Reading
Berkshire, England
Aston University
Birmingham, England
Comments