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Doctor of Philosophy [Ph.D] [Infection and Immunity] From Cardiff University

Cardiff, WalesLocation

UniversitySchool type

Estd1883established year

24245enrollment

Public

8.1/10

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Doctor of Philosophy [Ph.D] (Infection and Immunity)

STEM Course

4 years

Full Time

On Campus

Field of Study:

University allocates places on a first-come, first-served basis, so students are recommended to apply as early as possible.

Since the inhibition of phosphinositide-3-kinase ? (PI3K?) is known to result in the overall increase of cell surface expression of L-selectin in CTLs and other types of leucocytes (1, 2), we propose to study the potential pathways linking PI3K? inhibition and L-selectin expression in host immune responses against viral infections.
The leucocyte restricted homing molecule L-selectin has not been considered an important molecule on influenza-specific CTLs since expression is downregulated following T cell activation and is low on CTLs harvested from infected lungs.Ê
However, Dr Ager has shown that L-selectin is re-expressed on influenza-specific CTLs before lymph node egress and L-selectin is essential for virus clearance since L-selectin null CTLs cannot control influenza infection despite being activated in lymph nodes.Ê
Moreover, L-selectin enhanced CTLs expressing a shedding-resistant mutant of L-selectin, which do not downregulate L-selectin following activation (L?P) are superior in controlling influenza infection.

Academic Requirements:

Applicants should complete a bachelor’s degree or masters degree in relevant subject
Official transcripts of all the previous academic experience
Students should provide evidence of previous research experience

English Language Requirements:

IELTS Academic: 6.5 minimum overall with minimum of 5.5 in each subskill
PTE Academic: Atleast 69 overall with minimum of 59 in communicative skills
TOEFL IBT: minimum 90 overall with scores of 17 in writing, 17 in listening, 18 in reading and 20 for speaking

Indian Student Specific Requirements:

Program	Delivery Type	Duration
Ph.D BBSRC SWBIO DTP funded PhD studentships in Biosciences (9 projects)	full time	4 years

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