Is IISc equal to IIT?

No, IISc and IIT are not equal. Here are a few core differences between IISc and IIT.

• There are 23 IIT colleges across the country, whereas there’s just one IISC university.
• While you can get admission at IIT after completing high school, IISC provides only one course to students for pursuing right after they complete high school- Bachelor of Science
• IITs primary purpose is to build technical manpower for nation-building whereas IISC focuses on core scientific research or becoming a physicist or scientist.
• IIT graduates are open to studying different fields for example MBA or even starting their own ventures whereas IISC students mostly prepare themselves for research-oriented jobs.
• IIT focuses on the holistic development of its students with many many clubs and groups to pursue hobbies. There are also grand tech and cultural fests like Rendezvous and Techfest, IISc on the other hand has no such events or activities.
• IIT helps you become employable in the job market whereas IISC is for students who have a passion for science and want to pursue research and doctorates after graduation.
• IISC has two additional exams which are KVPY and NEET UG apart from the 2 common GATE and JEE. 

All in all, IISc and IIT are miles apart and have many points of difference.